• Curr Pain Headache Rep · Feb 2012

    Review

    Dependent behavior in patients with medication-overuse headache.

    • Jong-Ling Fuh and Shuu-Jiun Wang.
    • Department of Neurology, the Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan. jlfuh@vghtpe.gov.tw
    • Curr Pain Headache Rep. 2012 Feb 1;16(1):73-9.

    AbstractTwo thirds of patients with medication-overuse headache (MOH) fulfilled criteria for dependence on acute symptomatic treatments for pain, not exclusive of psychoactive medications, based on the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders. Several questionnaires have been used to assess dependent behavior in patients with MOH. Findings regarding underlying psychological profiles of dependence and MOH are not consistent. Nevertheless, several neuroimaging, genetic, and neurobiological studies support the existence of the common pathophysiological features of dependence and MOH and suggest a link between them. This review highlights recent studies on the relationship between dependence and MOH. This issue is important because it implies a treatment strategy in managing patients with MOH by providing the treatment of dependence.

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