• Andrew D McInnes, Robert M Sutton, Alberto Orioles, Akira Nishisaki, Dana Niles, Benjamin S Abella, Matthew R Maltese, Robert A Berg, and Vinay Nadkarni.
• The Children's Hospital of Philadelphia, Department of Anesthesia and Critical Care Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, United States. mcinnesa@email.chop.edu
• Resuscitation. 2011 Aug 1;82(8):1025-9.

AimDuring adult cardiac arrest, rescuers frequently provide ventilations at rates exceeding those recommended by the American Heart Association (AHA). Excessive ventilation is associated with worse clinical outcome after adult cardiac arrest. This study is the first to characterize ventilation rate adherence to AHA guidelines during in-hospital pediatric cardiac arrest resuscitation.Patients And MethodsWe prospectively enrolled children and adolescents (≥8 years of age) who suffered a cardiac arrest in a pediatric intensive care unit (PICU) or emergency department (ED) of a tertiary-care pediatric hospital. Ventilation rate (breaths per minute [bpm]) was monitored via changes in chest wall impedance (CWI) recorded by defibrillator electrode pads during cardiopulmonary resuscitation (CPR).ResultsTwenty-four CPR events were enrolled yielding 588 thirty-second CPR epochs. The proportion of CPR epochs with ventilation rates exceeding AHA guidelines (>10 bpm) was 63% (CI(95) 59-67%), significantly higher than our a priori hypothesis of 30% (p<0.01). The proportion of CPR epochs with ventilation rates exceeding 20 bpm was 20% (CI(95) 17-23). After controlling for location of arrest and initial event rhythm, resuscitations that occurred on nights/weekends were 3.6 times (CI(95): 1.6-7.9, p<0.01) more likely to have a ventilation rate exceeding AHA guidelines.ConclusionsDuring in-hospital pediatric cardiac arrest, rescuers frequently provide artificial ventilations at rates in excess of AHA guidelines, with twenty percent of CPR time having ventilation rates double that recommended. Excessive ventilation was particularly common during CPR events that occurred on nights/weekends.Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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