• Brain & development · Oct 2009

    Case Reports

    A splenial lesion with transiently reduced diffusion in clinically mild encephalitis is not always reversible: A case report.

    • Yuji Hashimoto, Jun-ichi Takanashi, Keiko Kaiho, Katsunori Fujii, Toshiyuki Okubo, Setsuo Ota, and Yoichi Kohno.
    • Department of Pediatrics and Radiology, Teikyo University Chiba Medical Center, Chiba, Japan. sdgcr596@ybb.ne.jp
    • Brain Dev. 2009 Oct 1;31(9):710-2.

    AbstractThe MR imaging finding of a reversible splenial lesion with transiently reduced diffusion has been reported in patients with clinically mild encephalitis/encephalopathy, leading to a new clinical-radiological syndrome, clinically mild encephalitis/encephalopathy with a reversible splenial lesion. We recently experienced a 3-year-old boy with clinically mild encephalitis with a splenial lesion exhibiting transient reduced diffusion on admission. He recovered completely with no particular treatment within 2 weeks. Though the splenial lesion decreased in size, it was detected for over 5 months in T2-weighted imaging. It is suggested that a splenial lesion with transiently reduced diffusion in clinically mild encephalitis/encephalopathy is not always reversible, and could result in gliosis.

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