• Georg Goldmann, Yaroslava Holoborodska, Johannes Oldenburg, Nico Schaefer, Tobias Hoeller, Jens Standop, Joerg C Kalff, Andreas Hirner, and Marcus Overhaus.
• Institute for Experimental Hematology and Transfusion Medicine, University of Bonn, Bonn, Germany.
• Am. J. Surg. 2010 May 1;199(5):702-7.

BackgroundThe aim of the current study was to investigate perioperative management and outcome of surgery in hemophiliacs.MethodsFifty-five hemophiliacs underwent surgery (appendectomy, cholecystectomy, inguinal hernia repair, hemorrhoidectomy). Surgical procedures in hemophiliacs and matched pairs were analyzed for duration of surgery, drainages, hospital stay, factor use (VIII, IX), and complications. Factor substitution was analyzed. Mann-Whitney U and Kruskal-Wallis tests were used (P < .05).ResultsNo significant differences were found for duration of drains and operation time in hemophiliacs versus matched pairs. Significance for duration of hospital stay compared with controls was found in hemophiliacs for appendectomy, inguinal hernia repair, and hemorrhoidectomy but not for cholecystectomy. In both groups, complications were low without significant differences.ConclusionsThis study found no significant differences in perioperative data and postoperative outcome in hemophiliacs compared with nonhemophiliacs due to the excellent perioperative interdisciplinary management at our Hemophilia Center with prolonged hospital stay in hemophiliacs.Copyright 2010 Elsevier Inc. All rights reserved.

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