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Stereotact Funct Neurosurg · Jan 2010
Case ReportsResponse to sham and active gamma ventral capsulotomy in otherwise intractable obsessive-compulsive disorder.
- F Gouvea, A Lopes, B Greenberg, M Canteras, A Taub, M Mathis, and E Miguel.
- Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil. fernando.sauerbronn @ gmail.com
- Stereotact Funct Neurosurg. 2010 Jan 1;88(3):177-82.
AbstractThis case regards a 34-year-old woman with severe and refractory obsessive-compulsive disorder, who was enrolled in a double-blind, randomized controlled trial of radiosurgery. She was at first submitted to a sham radiosurgical procedure, and 1 year later to an active intervention. Opposite clinical responses were observed in the follow-up of these different phases. During the sham surgery follow-up, no improvements were observed, but a remarkable amelioration was seen a few months after the active procedure. Detailed descriptions of psychopathological changes and neuroimaging findings as well as a discussion regarding the surgical technique are provided.
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