• Journal of neurosurgery · Jul 2016

    Case Reports

    The GNAQ in the haystack: intramedullary meningeal melanocytoma of intermediate grade at T9-10 in a 58-year-old woman.

    • Michael Hoffmann, Christian Koelsche, Marcel Seiz-Rosenhagen, Sabine Mai, Frank Lohr, David Reuss, Frederik Wenz, Christoffer Gebhardt, and Frank A Giordano.
    • Departments of 1 Radiation Oncology.
    • J. Neurosurg. 2016 Jul 1; 125 (1): 53-6.

    AbstractMeningeal melanocytomas are rare tumors. They are derived from leptomeningeal melanocytes and predominantly occur along the spine and the posterior fossa. Here, the authors report a case of intramedullary melanocytoma of intermediate grade in a 58-year-old female patient who was initially misdiagnosed with malignant melanoma until mutational analyses of a panel of genes associated with melanotic tumors led to reclassification.

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