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- Harsh Sharma, Daljit Singh, Puneet Pooni, and Urmil Mohan.
- Department of Pediatrics, Indira Gandhi Memorial Hospital, Male, Maldives. dr_harsh75@yahoo.co.in
- J. Trop. Pediatr. 2009 Dec 1;55(6):393-5.
ObjectivesTo determine incidence, related factors, outcome, bacterial organisms and their sensitivity patterns with regard to ventilator-associated pneumonia (VAP) in children.SettingLevel III PICU of a tertiary care center.DesignProspective cohort study.MethodsChildren in the age group of 1 month to 15 years, admitted to the pediatric intensive care unit requiring ventilatory support (V.I.P.BIRD infant-Pediatric ventilator) for at least 48 h. Clinical criteria used to define VAPs were the same as used by and Elward et al. and Salata et al.ResultsForty patients met the inclusion criteria and 8 (20%) had VAP. The risk factor significantly related with development of VAP was the use of H(2) blockers (Ranitidine) for >2 days. All other related factors were not significantly related to occurrence of VAP.ConclusionUse of H(2) blockers (Ranitidne) is associated with higher incidence of VAP in children.
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