• Raffaele Pugliese, Marco Boniardi, Stefano de Carli, Fabio Sansonna, Andrea Costanzi, Dario Maggioni, Giovanni C Ferrari, Stefano Di Lernia, Paola Loli, and Erika Grossrubatscher.
• Department of Surgery, Niguarda Hospital, Milan, Italy.
• J Laparoendosc Adv Surg Tech A. 2008 Aug 1;18(4):588-92.

BackgroundThis study was undertaken to evaluate the outcomes of the simultaneous bilateral laparoscopic adrenalectomy.Materials And MethodsThis was a retrospective study, including 11 patients with bilateral adrenal lesions, affected by Cushing's syndrome (n=2), Cushing's disease (n=6), pheochromocytoma (n=2), and 1 adrenocorticotrophin-hormone-dependent hypercortisolism of unknown origin.ResultsElevan bilateral adrenalectomies were carried out by the laparoscopic approach with no conversions. The operations were performed in 7 cases by the lateral transperitoneal adrenalectomy (LTLA), in 3 by the posterior approach (PRA), and in 1 by the combined approach. The mean size of the masses was 5 cm. (range, 4-13). The average operating time was 245 minutes for LTLA and 218 minutes for PRA (P<0.05). The estimated mean blood loss was 87+/-36 mL (range, 20-150). No patients required transfusions. The mean hospital stay was 5+/-1.8 days (range, 4-7). The mean follow-up was 34 months (range, 2-96).ConclusionsOur study confirms that the bilateral adrenalectomy by the minimally invasive technique is safe and effective, affording acceptable blood loss and morbidity with a short hospital stay.

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