• Phytother Res · Aug 2003

    Evaluation of antitussive potential of Ionidium suffruticosam Ging. (Violaceae) extract in albino mice.

    • R Boominathan, B Parimala Devi, and Subhash C Mandal.
    • Division of Pharmacognosy & Phytochemistry, Department of Pharmaceutical Technology, Faculty of Engineering & Technology, Jadavpur University, Calcutta, India.
    • Phytother Res. 2003 Aug 1;17(7):838-9.

    AbstractThe present study was carried out to evaluate the antitussive potential of methanol extract of Ionidium suffruticosam Ging. (Violaceae) which was investigated for its effect on a cough model induced by sulfur dioxide gas in albino mice. It exhibited significant dose-dependent antitussive activity when compared with the control, 250 and 500 mg/kg (p.o.) of the extract showing 28.37% and 54.16% inhibition of the cough with respect to control group. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototype antitussive agent.Copyright 2003 John Wiley & Sons, Ltd.

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