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Journal of neurotrauma · Jun 2005
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialEfficacy of standard trauma craniectomy for refractory intracranial hypertension with severe traumatic brain injury: a multicenter, prospective, randomized controlled study.
- Ji-Yao Jiang, Wei Xu, Wei-Ping Li, Wen-Hui Xu, Jun Zhang, Ying-Hui Bao, Yu-Hua Ying, and Qi-Zhong Luo.
- Department of Neurosurgery, Renji Hospital, Shanghai Second Medical University, Shanghai, People's Republic of China. Jiangjyb@online.sh.cn
- J. Neurotrauma. 2005 Jun 1;22(6):623-8.
AbstractTo compare the effect of standard trauma craniectomy (STC) versus limited craniectomy (LC) on the outcome of severe traumatic brain injury (TBI) with refractory intracranial hypertension, we conducted a study at five medical centers of 486 patients with severe TBI (Glasgow Coma Scale score 0.05). The results of the study indicate that STC significantly improves outcome in severe TBI with refractory intracranial hypertension resulting from unilateral frontotemporoparietal contusion with or without intracerebral or subdural hematoma. This suggests that STC, rather than LC, be recommended for such patients.
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