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- Palle Toft and Torben Gilsaa.
- Odense Universitetshospital, Anaestesiologisk-intensiv Afdeling V, Odense C. palle.toft@ouh.fyns-amt.dk
- Ugeskr. Laeg. 2007 Feb 19;169(8):692-5.
AbstractAcute renal failure (ARF) is characterized by a sudden increase in plasma creatinine and a decrease in urine flow. ARF is caused by multiple factors of which the most important are hypovolemia, hypotension, septic mediators and nephrotoxic agents. ARF is observed in 10-23% of critically ill patients. The mortality of critically ill patients in whom ARF has developed is 50-70%. If the patient survives, the recovery of renal function is 90-95%. Non-dialytic therapy is early volume resuscitation whereas furosemid may worsen ARF. At the present time the dialytic therapy of choice in ICU patients with ARF is continuous renal replacement therapy (CRRT).
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