• Cíntia Reina Grisan Tomal, Ana Gabriela Padua Dias da Silva, Américo Massafuni Yamashita, Pamela Vieira de Andrade, Márcia Tamiko Hirano, Maria Angela Tardelli, and Helga Cristina Almeida Silva.
• Anesthesiology, Pain, and Intensive-care Medicine Course, UniversidadeFederal de São Paulo, SP, Brazil.
• Rev Bras Anestesiol. 2012 Mar 1;62(2):154-72.

Background And ObjectivesDue to its pharmacological characteristics, sevoflurane is the ideal anesthetic for short-duration procedures. There are two brands of sevoflurane in the Brazilian market, Sevocris® and Sevorane®, with different formulations and packaging. The objective of this study was to assess whether there are differences between the two anesthetics regarding induction, maintenance, recovery, and consumption.MethodsOne hundred and thirty children were included, divided into two groups according to the brand used: Group 1 was assigned to sevoflurane Cristália® and Group 2 to sevoflurane Abbott®. The following parameters were assessed: heart rate, systolic and diastolic blood pressure, fraction of inspired and expired sevoflurane, BIS values, tympanic temperature, induction and recovery time, agitation upon awakening measured by the PAED scale, and anesthetic consumption by weighing the vaporizers. Anesthesia was induced with 1 MAC and increased every three breaths at 0.5 MAC, up to 3 MAC.ResultsThere was no difference between groups regarding the duration of the procedure, the anesthesia, and the parameters evaluated at induction. In Group 1, the number of children who required additional bolus of sevoflurane for anesthesia maintenance was higher than in Group 2 (p<0.05). The fraction of inspired and expired sevoflurane at the end of the procedure was lower in Group 1 (p<0.001). Upon awakening, BIS value was lower in Group 1 (p=0.045). Other parameters evaluated in recovery showed no difference between groups. The use of anesthesia was similar between groups.Copyright © 2012 Elsevier Editora Ltda. All rights reserved.

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