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Anesthesia and analgesia · Oct 2001
Case ReportsThe long-term antinociceptive effect of intrathecal S(+)-ketamine in a patient with established morphine tolerance.
- S Sator-Katzenschlager, E Deusch, P Maier, A Spacek, and H G Kress.
- Department of Anesthesiology and Intensive Care B, University of Vienna, Vienna, Austria. sabine.sator@univie.ac.at
- Anesth. Analg. 2001 Oct 1;93(4):1032-4, table of contents.
ImplicationsOur report describes for the first time the continuous long-term intrathecal application of S(+)-ketamine in a patient with chronic pain and morphine tolerance. Intrathecally applied S(+)-ketamine led to a significant pain reduction and consecutively reduced the doses of intrathecal morphine required for pain relief even several weeks after the cessation of the 24-day period of intrathecal S(+)-ketamine administration.
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