• Mahnoush Momeni, Farhad Hafezi, Hossein Rahbar, and Hamid Karimi.
• Motahary Burn and Reconstructive Centre, Iran University of Medical Sciences, Tehran, Iran.
• Burns. 2009 Feb 1;35(1):70-4.

AimTo study the efficacy of silicone gel applied to hypertrophic burn scars, in reducing scar interference with normal function and improving cosmesis.MethodsA randomised, double-blind, placebo-controlled trial involving 38 people with hypertrophic burn scars. Each scar was divided into two segments; silicone gel sheet was applied randomly to one of the two and placebo to the other. Participants were seen again after 1 and 4 months. Their data and wound characteristics were collected using the Vancouver scar scale.ResultsThe median age of participants was 22 years (1.5-60 years) and 16 were male; 4 did not attend follow-up and were excluded from the study. There were no significant differences in baseline characteristics. Although after 1 month all scar scale measures were lower in treated areas, only the vascularity scale was significantly different between the two areas. After 4 months, all scale measures were significantly lower in the silicone gel group than in the control group, except for the pain score.ConclusionSilicone gel is an effective treatment for hypertrophic burn scars.

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