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Clinical Trial
Splenic Doppler resistive index for early detection of occult hemorrhagic shock after polytrauma in adult patients.
- Francesco Corradi, Claudia Brusasco, Alessandro Garlaschi, Gregorio Santori, Antonella Vezzani, Paolo Moscatelli, and Paolo Pelosi.
- Dipartimento di Emergenza e Accettazione, IRCCS-Azienda Ospedaliera Universitaria-IST, Genova, Italy. francescorradi@gmail.com
- Shock. 2012 Nov 1;38(5):466-73.
AbstractThe objective of this study was to evaluate whether direct assessment of splenic circulation by splenic Doppler resistive index (Doppler RI) is a clinically useful noninvasive method for an early detection of occult hemorrhagic shock after polytrauma in adult patients. Splenic Doppler RI was measured in 49 hemodynamically stable adult patients admitted to the emergency department because of polytrauma. Renal Doppler RI was also determined in 20 patients. Spleen size, Injury Severity Score, systolic blood pressure, heart rate, blood lactate, standard base excess, pH, hemoglobin, and inferior vena cava diameter values were recorded at admission and at 24 h. Patients were grouped according to whether signs of hemorrhagic shock did (n = 22) or did not (n = 27) occur within the first 24 h from admission. Patients who developed hemorrhagic shock had significantly higher splenic and renal Doppler RI, higher Injury Severity Score, and lower standard base excess at admission. By multivariate logistic regression, splenic Doppler RI resulted to be a predictor of hemorrhagic shock development within the first 24 h from admission. Splenic Doppler RI may represent a clinically useful noninvasive method for early detection of occult hemorrhagic shock and persistent occult hypoperfusion after polytrauma in adult patients.
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