• Mehdi Yahia-Cherif, Isabelle Delpierre, Sergio Hassid, and Olivier De Witte.
• Department of Neurosurgery, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: mehdiyc@gmail.com.
• World Neurosurg. 2016 Apr 1; 88: 497-502.

ObjectiveThe purpose of this study is to demonstrate the possible bony regrowth of the sella after transsphenoidal surgery without any intraoperative sellar reconstruction.MethodsRadiologic findings of the sella were reviewed in patients with pituitary tumors treated by transsphenoidal surgery. In 17 patients who had postoperative cranial computed tomography scans, bony regeneration of the sellar floor was evaluated by comparing immediate and late postoperative scans. The bony opening reduction was measured in transverse and sagittal planes.ResultsThe median bony opening diameter in the transverse plane was 8.8 mm (interquartile range [IQR] 5.7-11.4) on the first scan and 4.2 mm (IQR 0.8-6.8) on the second scan. In the sagittal plane, it was 4.8 mm (IQR 1.8-6.8) on the first scan and 2.9 mm (IQR 1.6-3.9) on the second scan. These changes occurred in a median time of 36 months (IQR 22-42). There was a statistically significant decrease of the bony opening diameters in both the transverse and sagittal planes (P < 0.0001 and P = 0.0004, respectively). Bone regeneration was observed in 16 of the 17 patients (approximately 94%).ConclusionThere is a natural bony regeneration of the sella after transsphenoidal pituitary surgery.Copyright © 2016 Elsevier Inc. All rights reserved.

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