• Am. J. Obstet. Gynecol. · Feb 2012

    Review

    Challenges in defining and classifying the preterm birth syndrome.

    • Michael S Kramer, Aris Papageorghiou, Jennifer Culhane, Zulfiqar Bhutta, Robert L Goldenberg, Michael Gravett, Jay D Iams, Agustin Conde-Agudelo, Sarah Waller, Fernando Barros, Hannah Knight, and Jose Villar.
    • Departments of Pediatrics and of Epidemiology, Biostatistics, and Occupational Health, McGill University Faculty of Medicine, Montréal, Québec, Canada.
    • Am. J. Obstet. Gynecol. 2012 Feb 1;206(2):108-12.

    AbstractIn 2009, the Global Alliance to Prevent Prematurity and Stillbirth Conference charged the authors to propose a new comprehensive, consistent, and uniform classification system for preterm birth. This first article reviews issues related to measurement of gestational age, clinical vs etiologic phenotypes, inclusion vs exclusion of multifetal and stillborn infants, and separation vs combination of pathways to preterm birth. The second article proposes answers to the questions raised here, and the third demonstrates how the proposed system might work in practice.Copyright © 2012 Mosby, Inc. All rights reserved.

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