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- Elchanan Fried, Charles Weissman, and Charles Sprung.
- Department of Internal Medicine and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel. elchananf@hadassah.org.il
- Curr Opin Crit Care. 2011 Aug 1;17(4):396-401.
Purpose Of ReviewPostoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden.Recent FindingsWe review epidemiologic data and clinical tools presented in multiple current studies, which may help lower incidence and improve outcome of postoperative sepsis.SummaryThe incidence of postoperative sepsis has not declined over the past years, although mortality is trending downwards. Several biochemical and genetic markers may allow early diagnosis. Prevention and prompt treatment may lower mortality.
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