• Gen Hosp Psychiatry · Nov 2010

    Case Reports

    Duloxetine treatment of long-term ketamine abuse-related lower urinary tract symptoms: a case report.

    • Jia-Yu Chao and Hwa-An Shai.
    • Department of Psychiatry, Taichung Armed Forces General Hospital, Taiping City, Taiwan, Republic of China.
    • Gen Hosp Psychiatry. 2010 Nov 1;32(6):647.e5-6.

    ObjectiveTo report a case of ketamine abuse-related lower urinary tract symptoms (LUTS) in a depressed patient, who was successfully treated with duloxetine.Case ReportA 19-year-old woman with long-term (3 years) daily ketamine abuse had developed moderate depressive symptoms after forced cessation of ketamine use, together with severe LUTS of 3 months' duration. Urinary analysis and culture revealed negative results, and treatment with antibiotics was unsuccessful. Ketamine abuse-related LUTS were suspected and duloxetine was prescribed at 60 mg daily. After 2 weeks, the symptoms of depression and LUTS had been relieved.ConclusionsDuloxetine can be considered as one of the therapeutic drugs of choice for depressive patients with significant LUTS.Copyright © 2010 Elsevier Inc. All rights reserved.

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