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Letter Case Reports
QT interval prolongation associated with venlafaxine administration.
- Konstantinos Letsas, Panagiotis Korantzopoulos, Loucas Pappas, Dimitrios Evangelou, Michalis Efremidis, and Fotis Kardaras.
- Int. J. Cardiol. 2006 Apr 28;109(1):116-7.
AbstractA significant number of non-antiarrhythmic drugs including psychotropic agents have been shown to prolong cardiac repolarization increasing the risk for torsade de pointes ventricular tachycardia. We briefly describe a 60-year-old woman who admitted to the hospital due to hypertension and mild dyspnea having a prolonged QT interval (QTc: 582 ms). The patient had a known history of depression treated with venlafaxine. The QT interval normalised a few days after cessation of the antidepressant agent. This is the first report of venlafaxine-induced QT interval prolongation.
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