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Randomized Controlled Trial
Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.
- Arlene C Seña, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H Martin, Peter Leone, Linda McNeil, and Edward W Hook.
- Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. idrod@med.unc.edu
- Clin. Infect. Dis. 2013 Feb 1;56(3):420-2.
AbstractPersistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.
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