• Pediatr Crit Care Me · Nov 2011

    Case Reports

    The persistent thrombus: complications, diagnosis, and novel treatment intervention.

    • John Moua, Eliezer Nussbaum, Stephen G Romansky, Anthony D Becker, and Inderpal S Randhawa.
    • Miller Children's Hospital, Long Beach, CA, USA.
    • Pediatr Crit Care Me. 2011 Nov 1;12(6):e416-9.

    ObjectiveTo review the findings and discuss the implications of the topic of pharmacomechanical thrombolysis in pediatric patients with persistent thrombus.DesignA pediatric case presentation with a brief literature review on treatment of venous thrombosis and pharmacomechanical thrombolysis.InterventionsNone.Main ResultsThrombotic events refractory to standard medical and surgical care remain a life-threatening clinical challenge in the pediatric population. Research on persistent deep venous thrombosis and treatment modalities is limited. We present a pediatric patient with a history of malignant osteosarcoma who was diagnosed with deep venous thrombosis. Despite appropriate anticoagulation therapy, the thrombus remained persistent. Pharmacomechanical thrombolysis was utilized and proved to be an effective method in providing diagnosis and treatment.ConclusionPharmacomechanical thrombolysis is a valuable and effective method in providing diagnosis and treatment of persistent thrombus.

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