• Curr Opin Crit Care · Feb 2013

    Review

    Cardiopulmonary interactions in acute lung injury.

    • Gregory A Schmidt.
    • Division of Pulmonary Diseases, Critical Care, and Occupational Medicine, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA. Gregory-a-schmidt@uiowa.edu
    • Curr Opin Crit Care. 2013 Feb 1;19(1):51-6.

    Purpose Of ReviewThrough shared anatomy, pressures, and endothelial connections, the respiratory and cardiovascular systems affect each other in complex but clinically important ways.Recent FindingsLung injury has clinically important circulatory effects, especially with regards to right ventricular function. Mechanical ventilation and PEEP produce a host of circulatory consequences, some beneficial, some life-threatening. At the same time, circulatory impairments and treatments can magnify the impact of lung failure.SummaryCardiopulmonary interactions underpin current views of fluid management and mechanical ventilation. Understanding cardiopulmonary interactions and their physiological basis has direct clinical relevance.

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