• Am. J. Obstet. Gynecol. · Jun 2002

    Randomized Controlled Trial Clinical Trial

    A randomized trial of postoperative wound irrigation with local anesthetic for pain after cesarean delivery.

    • Vanessa A Givens, Gary H Lipscomb, and Norman L Meyer.
    • Department of Obstetrics and Gynecology, University of Tennessee Health Science Center, Memphis, USA.
    • Am. J. Obstet. Gynecol. 2002 Jun 1;186(6):1188-91.

    ObjectiveThe purpose of this study was to investigate the efficacy of continuous local anesthetic infusion system for pain control after cesarean delivery.Study DesignThis was a randomized prospective double-blind study. Patients who underwent cesarean delivery had a pain system implanted subcutaneously after closure of the fascia. Patients were randomized to receive an infusion of either 0.25% bupivacaine (n = 20) or normal saline solution (n = 16) into the wound for 48 hours. Postoperative pain (determined with a visual analog scale) and postoperative morphine use were assessed at 12, 24, and 48 hours.ResultsThere were no significant differences in patient demographics or visual analog pain scores at any time interval between the bupivacaine versus the placebo group. However, narcotic requirements to produce this amount of pain relief were significantly less in patients who received bupivacaine infusion rather than normal saline solution at all time intervals.ConclusionThe continuous local anesthetic infusion system appears to be effective in reducing postoperative morphine use after cesarean delivery.

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