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Eur J Phys Rehabil Med · Mar 2008
Case ReportsHeterotopic ossification due to neuromuscular blocking agent in adult respiratory distress syndrome. A case report.
- M Zynnurodlu, G Kaymak Karatap, and V Sepycy.
- Department of Physical Medicine and Rehabilitation, Gazi University Medical Faculty, -6500 Bepevler, Ankara, Turkey. muratz@gazi.edu.tr
- Eur J Phys Rehabil Med. 2008 Mar 1;44(1):81-5.
AbstractHeterotopic ossification (HO) is the formation of mature bone in soft tissues, which can be seen either in cases of traumatic injury or nontraumatic conditions. HO is more commonly observed after a traumatic event, such as a spinal cord injury or head injury. Although less common, it can also be seen after nontraumatic neurological conditions, such as long term coma or neuromuscular blockade. Patients with adult respiratory distress syndrome (ARDS) are at risk of developing HO, due to a prolonged mechanical ventilation period and exposure to neuromuscular blocking agents. In this case report, the authors describe a 51-year-old woman with ARDS, whose HO developed after long-term sedation with neuromuscular blockade agents.
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