• Acta Anaesthesiol Scand · Aug 1992

    Randomized Controlled Trial Clinical Trial

    Prophylactic laryngo-tracheal aerosolized lidocaine against postoperative sore throat.

    • P Herlevsen, C Bredahl, K Hindsholm, and P K Kruhøffer.
    • Department of Anaesthesia, Aalborg Hospital, Denmark.
    • Acta Anaesthesiol Scand. 1992 Aug 1;36(6):505-7.

    AbstractA randomized, double-blind study was carried out on 193 ASA I-II surgical patients to assess the effect of aerosolized lidocaine on sore throat, hoarseness and cough in connection with tracheal intubation. The study group received aerosolized lidocaine 100 mg 2 min before tracheal intubation, using a spray. The control group received no spray. The patients underwent a standardized general anaesthesia. The patients were interviewed when leaving the recovery room and the next day in the ward. Specific questions were asked regarding sore throat, cough and hoarseness. There were no significant differences between the two groups, which suggests that topical anaesthesia of the mucosa of the upper airway is ineffective as a means of ameliorating airway complaints in connection with tracheal intubation.

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