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Randomized Controlled Trial Clinical Trial
Iontophoretically applied lidocaine reduces pain on propofol injection.
- P J Sadler, H M Thompson, P Maslowski, A Liddle, and D J Rowbotham.
- University Department of Anaesthesia, Leicester Royal Infirmary, UK.
- Br J Anaesth. 1999 Mar 1;82(3):432-4.
AbstractWe have compared iontophoretically and locally applied lidocaine for relief of pain on propofol injection. Pain was assessed on insertion of a 20-gauge i.v. cannula and at 10-s intervals for 30 s after injection of propofol. Pain scores on cannulation were significantly less in the iontophoresis group (median 1.1) than in the sham (control) group (median 2.8) (P < 0.005). Pain after injection of propofol was significantly reduced at 10 (P < 0.002), 20 (P < 0.001) and 30 s (P < 0.001). We conclude that iontophoretically applied lidocaine decreased the pain of cannulation and propofol injection.
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