• Ned Tijdschr Tandheelkd · May 1996

    [Allergic reactions to local anesthetics].

    • D P Bruynzeel.
    • Afdeling Arbeidsdermatologie/Dermato allergologie, Academisch Ziekenhuis Vrije Universiteit te Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam.
    • Ned Tijdschr Tandheelkd. 1996 May 1;103(5):178-80.

    AbstractIn this article type I and type IV allergic reactions evoked by local anaesthetics are discussed. Contact dermatitis (type IV) reactions are mainly caused by local anaesthetics of the ester-type like procaine. Both contact dermatitis and anaphylactic reactions (type I) can be caused by anaesthetics of the amide-type (e.g. lidocaine), but these reactions are rare. Intra- and epicutaneous tests can be useful to prove allergy, but sometimes provocation tests are necessary. Many reactions are not caused by an allergic mechanism.

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