• Br J Anaesth · Dec 1991

    Randomized Controlled Trial Comparative Study Clinical Trial

    Comparison of plain and alkalinized local anaesthetic mixtures of lignocaine and bupivacaine for elective extradural caesarean section.

    • R Fernando and H M Jones.
    • Department of Anaesthetics, Royal Gwent Hospital, Newport.
    • Br J Anaesth. 1991 Dec 1;67(6):699-703.

    AbstractWe have examined a local anaesthetic mixture of 0.5% bupivacaine 10 ml and 2% lignocaine 10 ml with adrenaline 1 in 200,000, to which 8.4% sodium bicarbonate 2 ml was added, for extradural Caesarean section. The alkalinized mixture of local anaesthetics produced a block of more rapid onset and density than a mixture of bupivacaine and lignocaine alone (P less than 0.001).

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