• Keiko Toyoda and Hiroshi Oba.
• Department of Radiology, Teikyo University School of Medicine, Tokyo, Japan.
• Brain Nerve. 2011 Jan 1;63(1):5-15.

AbstractIn this study, we reviewed the findings of diagnostic imaging of cerebral vascular anomalies classified as cerebral cavernous malformation (CCM)/hemangioma, developmental venous anomalies (DVAs)/venous malformation (VM), and capillary telangiectasia. In addition, we described the imaging findings of cavernous sinus hemangioma and orbital hemangioma/vascular anomaly. CCM has 2 forms: a sporadic form characterized by isolated lesions and a familial form characterized by multiple lesions with an autosomal dominant mode of inheritance. Furthermore, CCMs are divided into 4 categories on the basis of magnetic resonance (MR) signal intensities on T1-, T2-, and gradient-echo (GRE) T2*-weighted images. In general, the lesion is hyper- or hypointense or has a core of reticulated signal intensity surrounded by a hypointense rim on conventional T2-weighted images. DVAs are characterized by the presence of a cluster of venous radicles that converge into a collecting vein, resulting in the typical caput medusae appearance of the lesion. Noncontrast T1- and T2-weighted images show flow voids and phase-shift artifact produced by the collecting vein of a DVA and by the large venous radicles of the caput medusae. Three-dimensional contrast-enhanced GRE T1-weighted imaging is useful for the assessment of morphological features of DVAs. In some cases, changes in parenchymal signal intensity within the drainage territory of the DVA are identified on T2-weighted image and fluid-attenuated inversion recovery (FLAIR) image. Capillary telangiectasias are small lesions and tend to appear as faintly hyperintense regions on T2-weighted image and faintly enhanced regions with a brush-like appearance. Results of susceptibility-weighted imaging (SWI) characteristically show this lesion as a hypointense mass. SWI is a novel imaging technique that exploits phase shifts to maximize sensitivity to differences between magnetic susceptibility between adjacent tissues. This technique is widely used with 3-T MR machines. SWI has improved the diagnosis of microbleeds, brain tumor, cerebrovascular disease, degenerative disease, etc. SWI is superior to GRE T2*-weighted imaging for determining hemosiderin, methohemoglobin, and deoxyhemoglobin contents. The sensitivity of SWI for determining the number of CCM lesions is significantly higher than that of GRE T2*-weighted imaging.

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