• Ned Tijdschr Geneeskd · Nov 2006

    [New medications; ziconotide].

    • A F Cohen and H van Bronswijk.
    • Centre for Human Drug Research, Zernikedreef 10, 2333 CL Leiden. ac@chdr.nl
    • Ned Tijdschr Geneeskd. 2006 Nov 4;150(44):2427-8.

    AbstractZiconotide is a synthetic analogue of a peptide found in the poison of the marine snail Conus magus. Ziconotide blocks N-type calcium channels, which play an important role in the transmission of pain signals in the dorsal ganglia of the spinal cord. The drug is indicated for 'severe chronic pain' and is administered intrathecally.

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