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Semin Respir Crit Care Med · Jun 2013
ReviewDNA viral infections complicating lung transplantation.
- Joseph P Lynch, Michael C Fishbein, John A Belperio, and David Sayah.
- Section of Infectious Diseases, Department of Medicine, Loyola University, Maywood, Illinois, USA.
- Semin Respir Crit Care Med. 2013 Jun 1;34(3):380-404.
AbstractDNA viruses with potential to cause complications after lung transplantation include the human Herpesviridae family consisting of cytomegalovirus (CMV), herpes simplex virus 1 and 2 (HSV-1, -2), varicella-zoster virus (VZV), human herpesvirus 6, 7, and 8 (HHV-6, -7, -8), and Epstein-Barr virus (EBV); the Polyomaviridae family consisting of BK virus and JC virus; and the Adenoviridae family consisting of more than 50 adenovirus subtypes. This is a diverse group of viruses with equally diverse immediate and long-term impacts on allograft function and clinical outcomes following lung transplantation. This article discusses the individual pathogens, their epidemiology and clinical manifestations, as well as treatment and preventive strategies in this era of antiviral treatment regimens.Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
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