• Anesthesia and analgesia · Mar 1997

    Randomized Controlled Trial Clinical Trial

    Nitrous oxide does not increase vomiting after dental restorations in children.

    • W M Splinter and L Komocar.
    • Department of Anaesthesia, Children's Hospital of Eastern Ontario, Ottawa, Canada.
    • Anesth. Analg. 1997 Mar 1;84(3):506-8.

    AbstractThe effect of nitrous oxide on postoperative vomiting was evaluated in 330 children who underwent outpatient dental restorations. There were two groups in this single-blind, randomized, controlled study. One group received nitrous oxide during their anesthetic, while the non-nitrous oxide group did not receive nitrous oxide at any time. Anesthesia was induced by inhalation with halothane or with propofol intravenously. The incidence of vomiting for 24 h after surgery was recorded. Overall, the incidence of vomiting was similar, with 30% of the control patients and 35% of the nitrous-treated patients vomiting after their anesthetic. However, in-hospital vomiting was less in the control group: 15% vs 24%, control versus nitrous oxide, P = 0.03. In conclusion, nitrous oxide does not alter postoperative vomiting after halothane anaesthesia for dental restorations in children.

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