• Xin Shi and Dong-xin Wang.
• Department of Anesthesia, First Hospital, Peking University, Beijing 100034, China. Email: caitlin_shixin@sina.com.
• Zhonghua Yi Xue Za Zhi. 2013 Nov 5;93(41):3272-5.

ObjectiveTo evaluate the effect of our prophylaxis job against awareness during general anesthesia and identify the effective methods. To analyze the risk factors of awareness.MethodsPatients who received general anesthesia requiring muscle relaxants were interviewed postoperatively. The cases with explicit recall (ER) were identified as the cases of awareness. The results of the patients were compared with a historical group of 2025 cases in a previous study.Results16 patients in the later group(6305 cases), 0.25%, had ER as compared with 1.38% in the earlier group (P < 0.05). 8330 patients were included in a Logistic analysis and factors associated with awareness were: TIVA technique (OR = 6.671), O2/N2O-based anesthesia >30 min (OR = 8.791), obvious intraoperative blood pressure fluctuation (OR = 9.995), midazolam as a premedication (OR = 0.060) , anesthetic gas monitoring (OR = 0.441).ConclusionAttentiveness on the knowledge of awareness and improvement in anesthetic management and monitoring were associated with a significantly reduced incidence of awareness as compared with a historical control population.

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