• Paediatric anaesthesia · Jan 2007

    Case Reports

    Intravenous paracetamol for postoperative analgesia in a 4-day-old term neonate.

    • Shruti Agrawal, John J Fitzsimons, Venetia Horn, and Andy Petros.
    • NICU and Pharmacy Department, Great Ormond Street Hospital, London WC1N 3JH, UK.
    • Paediatr Anaesth. 2007 Jan 1;17(1):70-1.

    AbstractThere are only a few clinical reports on the use of intravenous (i.v.) paracetamol in term neonates. This case report illustrates that when routes for administration of analgesics are restricted to i.v. only and when opioids are not indicated then i.v. paracetamol may be used. In our 4-day-old term infant, despite i.v. paracetamol for 48 h, the trough level during therapy was almost undetectable indicating rapid clearance. Although i.v. paracetamol is not licensed in this age group, it can prove very helpful when the only route of administration is intravenous.

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