• Anesthesia and analgesia · Feb 2011

    Case Reports

    The possible influence of pulmonary arterio-venous shunt and hypoxic pulmonary vasoconstriction on arterial sevoflurane concentration during one-lung ventilation.

    • Shinji Matsuse, Yoshiki Hara, and Takako Ohkura.
    • Department of Anesthesia, Kasukabe-chuo General Hospital, Midori-cho 5-9-4, Kasukabe, Saitama 344-0063, Japan. shinjimat@hotmail.com
    • Anesth. Analg. 2011 Feb 1;112(2):345-8.

    AbstractSevoflurane is widely used for its rapid onset and offset due to a lower blood/gas coefficient. However, involuntary movements, tachycardia, and hypertension have been observed in some patients despite a continuing constantly delivered concentration of sevoflurane during 1-lung ventilation (OLV), indicating the possibility of insufficient depth of anesthesia. We observed a temporary but obvious decrease in arterial sevoflurane concentration and pulse oximeter readings in a patient during OLV. This may have resulted in the depth of inhaled anesthesia being insufficient during OLV because the arterial sevoflurane concentration was lower than expected in spite of constantly delivered and inspiratory/expiratory sevoflurane concentrations.

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