• Hasan H Eker, Hester R Langeveld, Pieter J Klitsie, Martijne van't Riet, Laurents P S Stassen, Wibo F Weidema, Ewout W Steyerberg, Johan F Lange, Hendrik J Bonjer, and Johannes Jeekel.
• Department of Surgery, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, the Netherlands. h.eker@erasmusmc.nl
• Arch Surg. 2012 Mar 1;147(3):256-60.

HypothesisMesh repair is generally preferred for surgical correction of inguinal hernia, although the merits of endoscopic techniques over open surgery are still debated. Herein, minimally invasive total extraperitoneal inguinal hernioplasty (TEP) was compared with Lichtenstein repair to determine if one is associated with less postoperative pain, hypoesthesia, and hernia recurrence.DesignProspective multicenter randomized clinical trial.SettingAcademic research.PatientsSix hundred sixty patients were randomized to TEP or Lichtenstein repair.Main Outcome MeasuresThe primary outcome was postoperative pain. Secondary end points were hernia recurrence, operative complications, operating time, length of hospital stay, time to complete recovery, quality of life, chronic pain, and operative costs.ResultsAt 5 years after surgery, TEP was associated with less chronic pain (P = .004). Impairment of inguinal sensibility was less frequently seen after TEP vs Lichtenstein repair (1% vs 22%, P < .001). Operative complications were more frequent after TEP vs Lichtenstein repair (6% vs 2%, P < .001), while no difference was noted in length of hospital stay. After TEP, patients had faster time to return to daily activities (P < .002) and less absence from work (P = .001). Although operative costs were higher for TEP, total costs were comparable for the 2 procedures, as were overall hernia recurrences at 5 years after surgery. However, among experienced surgeons, significantly lower hernia recurrence rates were seen after TEP (P < .001).ConclusionsIn the short term, TEP was associated with more operative complications, longer operating time, and higher operative costs; however, total costs were comparable for the 2 procedures. Chronic pain and impairment of inguinal sensibility were more frequent after Lichtenstein repair. Although overall hernia recurrence rates were comparable for both procedures, hernia recurrence rates among experienced surgeons were significantly lower after TEP. Patient satisfaction was also significantly higher after TEP. Therefore, TEP should be recommended in experienced hands. Trial Registration  clinicaltrials.gov Identifier: NCT00788554.

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