• Billy B Kristensen, Yvonne H Rasmussen, Marianne Agerlin, Monica W Topp, Marianne O Weincke, and Henrik Kehlet.
• Department of Anesthesiology, Hvidovre University Hospital, Kettegård Allé 30, Copenhagen, Denmark. billy.kristensen@hvh.regionh.dk
• Acta Obstet Gynecol Scand. 2011 Oct 1;90(10):1121-5.

ObjectiveTo evaluate the analgesic effect of high-volume infiltration analgesia in urogenital prolapse surgery and provide a detailed description of the infiltration technique.DesignA randomized, double-blind, placebo-controlled study following the CONSORT criteria.SettingA university hospital.Patients48 patients undergoing posterior wall repair and perineorraphy.MethodsPatients received high-volume (26 ml) ropivacaine 1% with epinephrine (n=23) or saline (n=22) infiltration using a systematic technique ensuring uniform delivery to all tissues incised, handled or instrumented during the procedure.Main Outcome MeasuresPain and opioid requirements were assessed for 24 hours as well as time spent in the post-anesthesia care unit and time to first mobilization.ResultsPain at rest, during coughing and movement was significantly reduced for the first four hours with the high-volume local anesthetic infiltration technique (p<0.001-0.006). Opioid requirements and time spent in the post-anesthesia care unit were significantly reduced in the ropivacaine group (p<0.001 and p<0.001, respectively) as well as the time to first mobilization (p<0.014).ConclusionSystematic high-volume infiltration analgesia is an effective analgesic technique in patients undergoing posterior wall repair and perineorraphy, and improves early recovery.© 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2011 Nordic Federation of Societies of Obstetrics and Gynecology.

32 keywords...

hide…