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- Bosiljka Iskra, Marijana Zivko, and Petar Kes.
- Interni odjel, Opća bolnica Virovitica, Virovitica, Hrvatska.
- Acta Med Croatica. 2005 Jan 1;59(4):325-8.
AbstractMyopathy and rhabdomyolysis are rare adverse effects of treatment with hydroxymethylglutaryl-coA reductase inhibitors. The risk of adverse effects is increased with the concomitant use of statin and specific drugs that can induce myopathy, in patients with liver and renal function impairment, hypothyroidism and diabetes mellitus. The clinical picture of rhabdymyolysis with acute renal failure caused by the use of simvastatin in a 54-year-old patient with diabetes mellitus and hypertension is described.
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