• Hessam Sadatsafavi, Bahar Niknejad, Rana Zadeh, and Mohsen Sadatsafavi.
• Department of Design and Environmental Analysis, Cornell University, Ithaca, NY. Electronic address: hs825@cornell.edu.
• J Crit Care. 2016 Feb 1; 31 (1): 194-200.

PurposeEvidence shows that single-patient rooms can play an important role in preventing cross-transmission and reducing nosocomial infections in intensive care units (ICUs). This case study investigated whether cost savings from reductions in nosocomial infections justify the additional construction and operation costs of single-bed rooms in ICUs.Materials And MethodsWe conducted deterministic and probabilistic return-on-investment analyses of converting the space occupied by open-bay rooms to single-bed rooms in an exemplary ICU. We used the findings of a study of an actual ICU in which the association between the locations of patients in single-bed vs open-bay rooms with infection risk was evaluated.ResultsDespite uncertainty in the estimates of costs, infection risks, and length of stay, the cost savings from the reduction of nosocomial infections in single-bed rooms in this case substantially outweighed additional construction and operation expenses. The mean value of internal rate of return over a 5-year analysis period was 56.18% (95% credible interval, 55.34%-57.02%).ConclusionsThis case study shows that although single-patient rooms are more costly to build and operate, they can result in substantial savings compared with open-bay rooms by avoiding costs associated with nosocomial infections.Copyright © 2015 Elsevier Inc. All rights reserved.

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