• Critical care clinics · Jul 2011

    Review

    High-frequency oscillatory ventilation in ALI/ARDS.

    • Sammy Ali and Niall D Ferguson.
    • Internal Medicine Program, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
    • Crit Care Clin. 2011 Jul 1;27(3):487-99.

    AbstractIn the last 2 decades, our goals for mechanical ventilatory support in patients with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) have changed dramatically. Several randomized controlled trials have built on a substantial body of preclinical work to demonstrate that the way in which we employ mechanical ventilation has an impact on important patient outcomes. Avoiding ventilator-induced lung injury (VILI) is now a major focus when clinicians are considering which ventilatory strategy to employ in patients with ALI/ARDS. Physicians are searching for methods that may further limit VILI, while still achieving adequate gas exchange.Copyright © 2011 Elsevier Inc. All rights reserved.

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