• Eur. J. Obstet. Gynecol. Reprod. Biol. · May 1995

    Randomized Controlled Trial Comparative Study Clinical Trial

    Labor pain relief using bupivacaine and sufentanil: patient controlled epidural analgesia versus intermittent injections.

    • E P Vandermeulen, H Van Aken, and J D Vertommen.
    • Department of Anesthesiology, Universitair Ziekenhuis Gasthuisberg, Leuven, Belgium.
    • Eur. J. Obstet. Gynecol. Reprod. Biol. 1995 May 1;59 Suppl:S47-54.

    ObjectivesTo determine whether the use of patient-controlled epidural analgesia (PCEA) versus intermittent injections (CIT) resulted in local anesthetic dose reduction.Study DesignPCEA and CIT using a mixture of 0.125% bupivacaine with sufentanil 1 or 0.75 microgram/ml were compared in 60 and 195 parturients, respectively. Assessments included pain scores, local anesthetic consumption, degree of motor blockade, type of delivery and neonatal outcome. Statistical analysis was done using Student's t test and Chi-squares.ResultsPCEA and CIT provided effective analgesia during labor and delivery. A higher dose of opioid significantly reduced the use of local anesthetic solution in PCEA-patients. There was no difference in motor blockade, type of delivery and neonatal outcome.ConclusionPatient-controlled epidural analgesia is an effective, safe and acceptable alternative to conventional intermittent epidural injections for pain relief during labor and delivery.

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