• Critical care clinics · Oct 2013

    Review

    Vancomycin-Resistant Enterococci.

    • Ethan Rubinstein and Yoav Keynan.
    • Section of Infectious Diseases, Department of Internal Medicine and Medical Microbiology, University of Manitoba, 543-645 Bannatyne Ave, Basic Medical Building, Winnipeg, Manitoba R3E 0J9, Canada. Electronic address: rubinste@cc.umanitoba.ca.
    • Crit Care Clin. 2013 Oct 1; 29 (4): 841-52.

    AbstractVancomycin-resistant enterococci (VRE) consist mainly of Enterococcus faecalis and E faecium, the latter mostly hospital-acquired. In addition, E gallinarum and E casseliflavus are intrinsically vancomycin-resistant and are community-acquired. VRE have become common in many hospitals throughout the world and, once established, are very difficult to eradicate. VRE are difficult to treat; therefore, infection control measures in hospitals are of prime importance in preventing the establishment of these pathogens. Most severe VRE infections will need combination therapy because many of the effective antimicrobial agents, when used alone, have only a bacteriostatic effect.Copyright © 2013 Elsevier Inc. All rights reserved.

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