• Emerg. Med. Clin. North Am. · Nov 2008

    Permissive hypercapnia.

    • Alex Rogovik and Ran Goldman.
    • Pediatric Research in Emergency Therapeutics (PRETx) Program, Division of Pediatric Emergency Medicine, Ambulatory Care Building, BC Children's Hospital, 4480 Oak Street, Vancouver, BC, Canada.
    • Emerg. Med. Clin. North Am. 2008 Nov 1; 26 (4): 941-52, viii-ix.

    AbstractMechanical ventilation using high tidal volume (VT) and transpulmonary pressure can damage the lung, causing ventilator-induced lung injury. Permissive hypercapnia, a ventilatory strategy for acute respiratory failure in which the lungs are ventilated with a low inspiratory volume and pressure, has been accepted progressively in critical care for adult, pediatric, and neonatal patients requiring mechanical ventilation and is one of the central components of current protective ventilatory strategies.

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