• J Am Osteopath Assoc · Sep 1999

    Review

    Alzheimer's disease diagnosis.

    • S T Dinsmore.
    • Center for Aging, University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, Stratford 08084-1504, USA. dinsmore@umdnj.edu
    • J Am Osteopath Assoc. 1999 Sep 1;99(9 Suppl):S1-6.

    AbstractThis section reviews some of the more prominent alternate causes of dementia that need to be excluded when pursuing a diagnosis of Alzheimer's disease. In practice, this exclusion cannot be done with 100% precision. Consequently, the accuracy of the clinical diagnosis of Alzheimer's disease is approximately 85%. Brain biopsy, which is seldom performed in practice, is the only method of moving diagnostic accuracy to near 100%. There is yet no intervention that halts or reverses the underlying pathophysiology of Alzheimer's disease, so the invasive brain biopsy is rarely justified to confirm a diagnosis.

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