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Expert Opin Pharmacother · Dec 2009
EditorialRivaroxaban, the first oral, direct factor Xa inhibitor.
- Nicholas Fassiadis.
- Expert Opin Pharmacother. 2009 Dec 1;10(18):2945-6.
AbstractVenous thromboembolism (VTE) is a major cause of death in hospitalized patients. In particular, patients undergoing elective major lower-limb orthopaedic surgery are at high risk of developing post-operative VTE. Rivaroxaban, a new oral anticoagulant, has been shown to be more effective than enoxaparin in reducing total and symptomatic VTE with similar major and non-major bleeding rates in patients undergoing elective total hip or total knee replacement.
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