• Hao Zhang, Shi Liang, Qing Chen, Wen Zhou, Jian-Peng Xiao, and Hong-Biao Chen.
• Guanlan People's Hospital, Baoan District, Shenzhen 518100, Guangdong, China.
• Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Oct 1;22(10):617-20.

ObjectiveTo look for the independent factors influencing the effect of cardiopulmonary resuscitation (CPR) in emergency department.MethodsThe data of patients involved in the study were retrieved from 72 network emergency hospitals in Shenzhen from September 2004 to January 2009. The data base was set up with EpiData software, according to questionnaires about cardiopulmonary arrest (CA) patients treated with CPR, and analyzed with SPSS 13.0 software. The binary Logistic regression was carried out with 8 factors which had emerged statistical significance through single factor analysis.ResultsA Logistic regression analysis on the factors influencing return of spontaneous circulation (ROSC) in emergency department showed the ventrical fibrillation [VF, odds ratio (OR)=3.071, P=0.000, 95% confidence interval (95% CI)=2.019-4.670] and pulseless electric activity (PEA, OR=1.730, P=0.036, 95% CI=1.036-2.890) were protective factors compared with asystole; electric shock was a protective factor (OR=1.574, P=0.015, 95% CI=1.093-2.265); adrenaline ≤4 mg group had higher likelihood of obtaining ROSC compared with group receiving ≥5 mg of adrenaline (OR=1.483, P=0.037, 95% CI=1.024-2.147); duration of CA before CPR was a risk factor (OR=0.961, P=0.000, 95% CI=0.946-0.976). A Logistic regression analysis on the factors influencing survival to admission in emergency department showed the VF was a protective factor compared with asystole (OR=2.013, P=0.002, 95% CI=1.299-3.121); adenine ≤4 mg group had higher likelihood of survival to admission compared with group ≥5 mg (OR=2.289, P=0.000, 95% CI=1.487-3.524); duration of CA before CPR was a risk factor (OR=0.951, P=0.000, 95% CI=0.933-0.969).ConclusionRhythm of heart, the duration of CA, electric shock and accumulated adrenaline dosage were independent influencing factors for ROSC in emergency department. Rhythm of heart, the duration of CA and accumulated adrenaline dosage were independent influencing factors for survival to admission in emergency department.

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