• Yasser Sakr, Cristina Elia, Luciana Mascia, Bruno Barberis, Silvano Cardellino, Sergio Livigni, Gilberto Fiore, Claudia Filippini, and V Marco Ranieri.
• Department of Anesthesiology and Intensive Care, Friedrich-Schiller-University, Erlanger Allee 103, 07743 Jena, Germany. yasser.sakr@med.uni-jena.de
• J Crit Care. 2012 Dec 1;27(6):714-21.

PurposeTo describe the epidemiology of obesity in a large cohort of intensive care unit (ICU) patients and study its impact on outcomes.MethodsAll 3902 patients admitted to one of 24 ICUs in the Piedmont region of Italy from April 3 to September 29, 2006, were included in this retrospective analysis of data from a prospective, multicenter study.ResultsMean body mass index (BMI) was 26.0 ± 5.4 kg/m(2): 32.8% of patients had a normal BMI, 2.6% were underweight, 45.1% overweight, 16.5% obese, and 2.9% morbidly obese. ICU mortality was significantly (P < .05) lower in overweight (18.8%) and obese (17.5%) patients than in those of normal BMI (22%). In multivariate logistic regression analysis, being overweight (OR = 0.73; 95%CI: 0.58-0.91, P = .007) or obese (OR = 0.62; 95%CI: 50.45-0.85, P = .003) was associated with a reduced risk of ICU death. Being morbidly obese was independently associated with an increased risk of death in elective surgery patients whereas being underweight was independently associated with an increased risk of death in patients admitted for short-term monitoring and after elective surgery.ConclusionsIn this cohort, overweight and obese patients had a reduced risk of ICU death. Being underweight or morbidly obese was associated with an increased risk of death in some subgroups of patients.Copyright © 2012 Elsevier Inc. All rights reserved.

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