• Clinics in chest medicine · Jun 2011

    Review

    Alternatives to lung transplantation: treatment of pulmonary arterial hypertension.

    • Paul A Corris.
    • Institute of Cellular Medicine, Newcastle University and Newcastle upon Tyne Hospitals NHS Foundation Trust, NE77DN, UK. Paul.corris@ncl.ac.uk
    • Clin. Chest Med. 2011 Jun 1;32(2):399-410.

    AbstractThe development of targeted therapies for pulmonary arterial hypertension currently based on prostaglandin, nitric oxide, and endothelin pathways has resulted in major advances in the treatment of patients with pulmonary arterial hypertension. This article reviews the current evidence that supports both the use of mono- and combination therapy. The article also considers the role of atrial septostomy in the treatment of pulmonary arterial hypertension, particularly as a bridge to transplantation. Finally, the article provides a review of the role and outcomes of pulmonary thromboendartertectomy for patients with chronic thromboembolic pulmonary hypertension.Copyright © 2011. Published by Elsevier Inc.

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