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J. Thromb. Thrombolysis · Jan 2014
Case ReportsDabigatran-associated subdural hemorrhage: using thromboelastography (TEG(®)) to guide decision-making.
- Ron Neyens, Nicole Bohm, Madelyne Cearley, Charles Andrews, and Julio Chalela.
- Department of Pharmacy, Medical University of South Carolina, Charleston, SC, USA.
- J. Thromb. Thrombolysis. 2014 Jan 1;37(2):80-3.
AbstractNovel oral anticoagulants present challenges and uncertainties in the management of hemorrhagic emergencies. An 84-year-old man taking dabigatran presented with a subdural hematoma requiring neurosurgical intervention. Routine coagulation assays were prolonged at admission and following administration of Factor VIII Inhibitor Bypassing Activity (FEIBA). Thromboelastography (TEG(®)) was utilized to assess clot dynamics prior to placement of a subdural drain, which was safely inserted despite a prolonged thrombin time (TT). Exclusive reliance on the TT may delay necessary interventions. TEG(®) may be a valuable tool to investigate hemostasis in patients on dabigatran requiring emergent procedures.
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